Meeting Banner
Abstract #3787

Intensity Inhomogeneity Correction in Human Brain Imaging at 7 Tesla Using SPM8

Ikuko Uwano1, Kohsuke Kudo1, Fumio Yamashita1, Jonathan Goodwin1, Tsuyoshi Metoki1, Satomi Higuchi1, Kenji Ito1, Makoto Sasaki1

1Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Morioka, Iwate, Japan

In ultra-high field 7 Tesla (T) MRI, signal intensity variation or inhomogeneity are caused by main magnetic field (B0) and RF field (B1) inhomogeneity, susceptibility effects, and inhomogeneous coil sensitivity. We tested a post-processing technique available with SPM8, for signal intensity correction of various scan sequences on 7 T MRI. We found that by using SPM8, signal inhomogeneity was successfully corrected and a reduction in signal non-uniformity between the subcortical and deep white matter was observed.

Abstract PDF Presentation Video

Keywords

according acquisitions addition advancement advantages although anal analyses assumed audience available became best bias biomedical bottom brain channel clinical close coefficient coil coils consisted contrast correct corrected correction correspond decrease decreased deep default defined deviation diameter discovery disorders distant division drop efficiency enabled enhanced entire evaluate evaluated examination examined fast field flight full future gradient half head healthy human included indicate inhomogeneity inhomogeneous institute intensities intensity intervals japan lesions manually markedly matrix medical middle namely needed noise nonparametric offers optimal original pairs part patient performance periphery placed possibly post processing proposed quadrature receive recent remarkable repetition represents researchers resolution respectively rows scanner sciences segment sensitivity several significantly slice slices smaller smoothness spatial spherical spin spoiled statistical steel subject successfully surface susceptibility table target tendencies transmit tumors ultra ultrahigh uniform uniformity validated variable variation various view volunteers white width women years