Effects of a Nutrient-Combination Diet on Cerebral Blood Flow, Metabolites Levels and Brain Diffusion in ApoE4 and ApoE Knockout Mice

Keywords

able abnormalities actively alternating anatomy animals anterior assess audience background beneficial blood brain capillary cardiovascular carriers carrying cerebral choline circular cofactors cognitive coil combination community conditions consumption containing contribute control decline decoupled decrease decreased dementia dependence detected determined development diet dietary diets diffusion diffusivity disease enhanced especially estimation exhibited fair field fish flow fractional framework funding genetic genotype glutamate gradient grant gray hypothesis indicate influence instead intake interestingly inversion involved knockout lipid major male management many measure medical membrane metabolism metabolite metabolites mice model month months mouse normalization nutrient nutrition omega overall particularly patients perfusion polarized positively precursors press prevent previously quantified radiology received recovery reduced reflect related researchers resembling resonator respectively restoring revealed risk robust role seem selenium seventh several shielded significantly slow spatial sporadic stimulate stimulation strains strongly studies successfully sufficient suggest suggesting synthesis system taken target tensor thalamus together tracts transporter treat type unaffected vascular water white wild