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Abstract #3600

The Neuroanatomic Difference in Grey Matter Among Post-Traumatic Stress Disorder, ObsessiveCcompulsive Disorder and Social Anxiety Disorder

Bochao Cheng1, Xiaoqi Huang1, Xun Yang2, Xinyu Hu1, Yajing Meng2, Shiguang Li1, Xiuli Wang2, Qiyong Gong1

1HMRRC.Department of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan province, China; 2West China Hospital of Sichuan University, Psychiatric department, Chengdu, Sichuan, China

It is the first study to compare the whole-brain based GMV among three anxiety disorders and HC participants. Our results demonstrate that PTSD have siginificant microstructure discrepancy with other three groups. No statastical siginificant difference in GMV can be found between OCD, SAD and HC group. Our finding show that PTSD might have different psychopatholgy circuit with OCD and SAD, which may give new proposal for the upcoming DSM CV and ICD-11.

Keywords

abnormal abstract according activity advanced algebra among anatomic anxiety applied association basis belong besides bilateral brain caps categories category cerebellum cerebral china classified clinical comparing compulsive control corrected correlation criterion debate decreased depression detachment diagnosed diagnostic differ direct disorder disorders distinct evaluated evidence expectations explore exponentiated function functional fundamental fusiform future gave generalize gong healthy hence homogeneity hospital hypothalamus increasing inferior issue journal letters lobe lobule manual mechanism mental middle miller near negative neural obsessive panic parietal participants past pathogenesis patient patients phobia post posterior prevalent process profile province psychiatric psychiatry publishing radiology recently regional registration relatively remains remove researches respectively resting revealed scale scales severity shared social statistical still stress structural studied symptom symptoms target temporal threshold traumatic treatment trend typical underline volume west yang