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Abstract #0345

Chronic Low Back Pain Patients Exhibit Distinct Patterns of Increased Resting Cerebral Blood Flow

Ashley D. Harris1, Ann M. Taylor2, Judith E. Hall2, Richard G. Wise1

1CUBRIC, School of Psychology, Cardiff University, Cardiff, United Kingdom; 2Department of Anaesthetics, Cardiff University, Cardiff, United Kingdom

Cerebral blood flow differences between chronic pain patients compared to healthy control was quantified. Regions that displayed significant difference in CBF and that have been previously shown to have difference in functional connectivity were then used as seed regions to examine alterations in connectivity between patients and controls.

Keywords

accelerate accepted acute administration ahead alterations anterior anxiety application applied arterial arthritis assist attentional back blood body bold brain capacity central cerebral chronic cluster cognitive compartment condition conditions consistent consistently control controls corrected cortex cortices density depression detect detected development diagnosis distinct division efficacy electric events examine examined exhibit fear field flow forming fourteen fusiform general generally hall identified implicated include included inferior involved kingdom lateral likely location long maps markers matrix mechanisms model modulation morbidities motor network networks occipital often osteoarthritis pain painful parietal part patient patients patterns peak physician pole post posterior primary print processes processing psychology pulsed quantified recently reduced regardless regional registered related responding resting restricted reveal revealing rheum robust scanning school secondary sensitive sensory significantly slices space spin stat statistic stimulation studies suggested suggesting summarized surgical table temporal term thalamus thirteen thumb tonic treatment treatments underlying understanding unique unlike view whole wise year