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Abstract #0554

Percutaneous Selective Laser Hippocampectomy for Treatment of Mesial Temporal Lobe Epilepsy Within an Interventional MRI Suite

Robert E. Gross1, 2, Amit Saindane, 23, Hiroumi D. Kitajima, 23, Bobbie Burrow, 24, Ashok Gowda5, Sherif G. Nour, 23

1Neurosurgery, Emory University School of Medicine , Atlanta, GA, United States; 2Emory Interventional MRI Program, Emory University Hospital , Atlanta, GA, United States; 3Radiology and Imaging Sciences, Emory University School of Medicine , Atlanta, GA, United States; 4Radiology and Imaging Sciences, Emory University Hospital , Atlanta, GA, United States; 5Visualase, Inc., Houston, TX, United States

Patients with refractory mesial temporal lobe epilepsy are candidates for surgical mesial temporal lobe resection. There is a growing trend toward more selective resections of the amygdala/hippocampus to improve cognitive outcomes. However, "selective amygdalo-hippocampectomy may still be complicated by collateral damage en-route to mesial temporal lobe structures. This report introduces a minimally invasive alternative via percutaneous selective laser hippocampectomy where laser fiber insertion in the hippocampus is confirmed/adjusted under MRI and followed by temperature-controlled targeted energy deposition under real-time MRI monitoring within a dedicated interventional MRI suite. Technical aspects, feasibility, safety, and MRI appearance of resultant ablation zones are described.

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Keywords

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