Imaging of Amide Proton Transfer (APT) and Nuclear Overhauser Effect (NOE) Using Chemical Exchange Rotation Transfer (CERT)

Keywords

actual affected albumin alternative although amide amides analyses anatomy appears application arrow asymmetric asymmetry audience avoids bearing bovine brain caused cert chemical comes comparing component concentration conclude confounding constant contrast contrasts contribution contributions core curves detect deviations difficult dips direct distinguish dominated double dynamic enhancement examining exchange exchangeable exchanging experimental features field fitted fitting frequencies frequency full good gore heterogeneous in vivo include indirectly instead interpretation interpreted inversion investigators irradiation isolates john labile likely little live longer macromolecular making mapping mark matrix metabolites metric modified noes note nuclear nutation offset offsets overlap peak peaks peptides phantom plot plots potentially power prepared press produce protein proton protons pulse pulsed pulses quantify quantitative rather recently recovery related relatively remove reported require ring rotation roughly saturation science sensitivity separation serum several shot side sides site sites slow slowly spectra spectral still strong studies subtraction system target tissues train transfer tumor tumors underlies upfield view water white