T2 Relaxation Dispersion Technique to Detect Intermediate and Fast Exchanging Protons in Metabolites and Proteins

Keywords

achieved acid advantages agents arrows audience brain broadening buffered category chemical choline common commonly concentration concentrations conducted contrast conversely curves defined degree detect detection develop developed diamagnetic difficult disadvantage dispersion dissolved distribution endogenous equations especially exchange exchangeable exchanging expected experiment extend fall fast field fitted fixed flex form frequencies frequency function funding generating gill grants hard horizontal important in vivo increasing indicate instance intensity intermediate investigators invisible johns keeping lactate length limit mapping matrix measured measuring meeting metabolite metabolites module molecules monitored nature needing opposed peak peaks phosphate physiological plotted pool popular power preparation presence propose protein proteins proton protons pulse pulses quantify quantifying radiological radiology rapidly rare readout receive recorded refocusing regime relationship repetition represent resonator resp respectively revealed room saturation science separation simple situation slice slow solute solutions spacing species spectra spectrum still strong support system table target temperature titrated train transfer transferred transmit tubes typical units varied volume water wave