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Abstract #3424

Combination of Perfusion and Diffusion-Weighted MRI for Functional Evaluation of Therapeutic Response of Lung Cancer

Yeun-Chung Chang1, Ang Yuan2, Chia-Hsien Cheng3, Yi Fang Chen4, Yi-Chien Lu1, Kua-Hung Cho5, Jyh-Horng Chen6

1Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, Taiwan; 2Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, Taiwan; 3Department of oncology, National Taiwan University, Taipei, Taiwan, Taiwan; 4Institute of Clinical Dentistry, National Taiwan University, Taipei, Taiwan, Taiwan; 5Instrumentation Resource Center, National Yang-Ming University, Taipei, Taiwan, Taiwan; 6National Taiwan University, National Taiwan University, Taipei, Taiwan, Taiwan

Combination of both DCE-MRI and DW-MRI provides more comprehensive understanding of change of internal tumor composition. Many preclinical studies have indicated that the addition of various types of antiangiogenic or antivascular therapy to single-dose or fractionated radiotherapy can synergistically improve the response of human and murine tumors to treatment.

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Keywords

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