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Abstract #3237

Deep Brain Stimulation fMRI with a Home-Made Two-Channel Tungsten Microwire Electrode

Hsin-Yi Lai1, John Robert Younce1, Yu-Chieh Jill Kao1, Yen-Yu Ian Shih1

1Experimental Neuroimaging Laboraory, Department of Neurology and Biomedical Research Imaging Center, University of North Carolina, Chapel Hill, NC, United States

This study demonstrates the feasibility of tungsten microwire electrode for DBS fMRI, showing reduced susceptibility artifact, sufficient flexibility and robust BOLD fMRI responses in rats. Similar frequency dependency was found under isoflurane anesthesia and -chloralose sedation.

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Keywords

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