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Abstract #3233

fMRI Study of Sound Pressure Level Encoding in the Different Subdivisions of Inferior Colliculus

Jevin W. Zhang1, 2, Condon Lau1, Joe S. Cheng1, 2, Iris Y. Zhou1, 2, Matthew M. Cheung1, Ed X. Wu1, 2

1Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong, Hong Kong SAR, China; 2Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong, Hong Kong SAR, China

In all mammals, the inferior colliculus (IC) is the major midbrain nucleus for integration of auditory information from the brainstem. It is composed of a central nucleus (CIC) adjacent to the external cortical nucleus (ECIC). One important piece of physical auditory information is intensity, which is customarily reported as sound pressure level (SPL). In our study, the BOLD signal changes increase with SPL in both the ECIC and CIC, but the slope in the ECIC is significantly higher than that in the CIC possibly due to a greater fraction of monotonic neurons in the ECIC.

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Keywords

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