Preliminary Evidence of Abnormalities in the Prefrontal Cortex of 10 Weeks Old Ts65Dn Mouse Model of Down Syndrome Using DKI-Cerebral Microenvironment Modeling.

Keywords

abnormal abnormalities acknowledgments acquisition aging alterations animal anisotropy application architecture audience authors axial axons behavior beyond biomedical brain bridge cause cerebral characteristics characterization characterized cognitive coherence common compartment compartments complexity confined confirmed consisting contributing correlation cortex cortical decreased demonstrating dendrites density derived despite developing development deviation diffusion diffusional diffusivity dimensionless disabilities distribution entire example exchanging exhibit extends fact foundation fractional frontal future generalizes genetic gradient heather house humans hunter idealized impairment in vivo indicators inferred infinitely info kurtosis lamination larger little long longitudinal male manually maria matrix maturation measure mechanisms medical medicine metrics mice minutes model modeling models morphological mouse narrow necessary nelson neural open orientations overall pilot plasticity post preliminary previously processing progressive project proposed published quantifying quantitative radial radiological radiology related relating represents resolution sample science several shape shot slices smaller software south statistical stems stress structure studied studies synaptic syndrome system table target thank thinner tissue units water weeks yields