Meeting Banner
Abstract #3048

Measurement of Reduced Lymphatic Flow Velocity Under Conditions of Obstructed Lymphatic Flow Using Spin Labeling Approach

Swati Rane1, Paula Donahue2, 3, Theodore F. Towse1, Sheila Ridner4, John C. Gore1, 5, Michael A. Chappell6, 7, Manus J. Donahue1, 8

1VUIIS, Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States; 2Vanderbilt Dayani Center for Health and Wellness , Vanderbilt University Med. Center, Nashville, TN, United States; 3Vanderbilt Physical Medicine and Rehabilitation, Vanderbilt University Med. Center, Nashville, TN, United States; 4School Of Nursing, Vanderbilt University, Nashville, TN, United States; 5Biomedical Engineering, Vanderbilt University, Nashville, TN, United States; 6Institute of Biomedical Engineering, University of Oxford, Oxford, OX, United Kingdom; 7John Radcliffe Hospital, Oxford Centre for Functional MRI of the Brain, Oxford, OX, United Kingdom; 8Psychiatry, Vanderbilt University, Nashville, TN, United States

This work tests the feasibility of our recently developed lymph spin labeling approach to study reduced lymphatic velocity in breast cancer treatment related lymphedema subjects

Abstract PDF Presentation Video

Keywords

abilities accordance account accounted adapted adiabatic affects approaches arrival assess audience axillary biomedical blood blue body bottom breast breathing cancer caused channel clinical coil common commonly compartment component compromised conditions context control cuff cuffed curves delayed dependence depicts describing detecting development diastolic disease displacement distortion engineering evaluate expand experiment extended extending extent fall fixed flow fluid function functional gaps gradient health healthy impaired impairment informed intervals inversion john kinetic kingdom knowledge known labeling local locate location lymph lymphatic magnetization manipulated measure measured measuring medicine model models motion node nodes noise note novel obstructed obstruction oncologists outline oxford patient patients physical physicists physiological pressure prevalent probability product proportional protocol psychiatry pulsed quantification quantitative questions radiological radiology readout receive recorded reduced removal representative residence residue resolution respiratory response rise risk scanned school sciences sensitivity several shape side simple simulated simulations spatial spin stage subject suppression system therapy torso understudied unlike vary velocity volunteers