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Abstract #3047

Simultaneous Measurement of Perfusion and BOLD Changes in Calf Muscle During Exercise

Jason K. Mendes1, Christopher J. Hanrahan1, Gwenael Layec2, Corey Hart2, Russell S. Richardson2, Vivian S. Lee3

1Radiology, University of Utah, Salt Lake City, UT, United States; 2Internal Medicine, University of Utah, Salt Lake City, UT, United States; 3School of Medicine, University of Utah, Salt Lake City, UT, United States

Perfusion and oxygenation in calf muscle have been shown to be beneficial in determining severity of peripheral arterial disease and monitoring response to therapeutic interventions. However, imperfections in the saturation/inversion pulses used in ASL sequences cause significant errors in the measurement of perfusion. This works demonstrates the feasibility of modeling these imperfections in the calculation of perfusion.

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Keywords

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