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Abstract #2950

Quantitative Correlations Between Gray Matter Volume and White Matter Tracts in Frontal and Occipital Regions in Preschool Children: Assessment Combined 3D T1WI and DTI

Xue Luo1, 2, Jie Gao1, Xianjun Li, 23, Mingxi Wan4, Jian Yang, 23

1Department of Radiology, The First Affiliated Hospital of Medical College, Xian Jiaotong University, Xi'an, Shannxi, China; 2School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shannxi, China; 3Department of Radiology, The First Affiliated Hospital of Medical College, Xian Jiaotong University, Xi'an, Shannxi , China; 4School of Life Science and Technology, Xi'an, Shannxi, China

The aim of this study is to combine 3D T1WI and DTI to primarily investigate the correlations between the variations of GM and WM in frontal lobe and occipital lobe during preschool period. FreeSurfer and MedINRI were used to analyze 3D T1WI and DTI data separately. The results of correlation analysis showed there were strong positive correlations between GM volume of frontal cortex, occipital cortex and numbers of fibers through these two cortexes and age. The correlation coefficients related with frontal cortex were all larger than them related with occipital cortex. This is the first study that demonstrated the positive relationship between GM volume in frontal cortex and occipital cortex and number of WM fibers through corresponding cortex in preschool children.

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Keywords

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