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Abstract #2765

Cost Efficient Small Animal Monitoring and Trigger Device for Clinical Scanners

Karl-Heinz Herrmann1, Norman Pfeiffer1, 2, Ines Krumbein1, Lutz Herrmann2, Jrgen R. Reichenbach1

1Medical Physics Group, Institute of Diagnostic and Interventional Radiology I, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany; 2Ernst-Abbe-Fachhochschule Jena, Jena, Germany

A cost efficient system to acquire a respiratory and cardiac monitoring signal for small animals like mice and rats is presented. The motion detection is based on a small pressure pad and the signal is converted and processed by an analog amplifier and filter circuit. The output in the range of Volts allows any kind of further visualization or sophisticated post-processing in hard- or software. Exemplarily the improved image quality of T2 weighted MR images are shown using the generated respiratory trigger in comparison to the untriggered images.

Keywords

abdominal access added allow almost already amplified amplifier analog anesthetic anesthetized animal animals artifact artifacts attenuating audience automate basic bias biomedical body bought build card cardiac caused cheap clearly clinical coil common components conduct conversion cost creation dedicated demand described detect detection device diagnostic digitized digitizer easily easy efficient either electrical electronic employing enabling especially excellent extensions field filter final frequencies function furthermore gains generation gradient handle hardware head heart histological holder increasing inherently instruments limited lock long longitudinal many mater medical mice mode monitoring motion mounting mouse necessary need next noise occasional opens oscilloscope output outside part parts pass placed position possibility post pressure processing quality radio rapid realized receive recording reduced regularly rejection removes respiration respiratory sacrifice scanner scanners schematic sensor separation serve several simply since slow software sophisticated stage steadily studies successful supply suppressed suppresses switch system taken target temperature threshold trends trigger tube unit varying vibration whole