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Abstract #2431

Waveguide Magnetic Resonance Elastography of the Heart

Anthony J. Romano1, Ria Mazumder2, Seongjin Choi3, Bradley Dean Clymer4, Richard White5, Arunark Kolipaka5

1Physical Acoustics, Naval Research Laboratory, Washington, DC, United States; 2Electrical and Computer Engineering, Ohio State University, Columbus, OH, United States; 3Radiology, The Ohio State University, Columbus, OH, United States; 4Electrical and Computer Engineering, The Ohio State University, Columbus, OH, United States; 5Radiology and Internal Medicine, Ohio State University Wexner Medical Center, Columbus, OH, United States

Previously, we implemented a method called Waveguide Elastography in the analysis of the orthotropic elastic parameters of the corticospinal tracts (CSTs) in the brains of five healthy volunteers. Here, we extend this method in the analysis of an ex-vivo, porcine heart. We used our method to evaluate the anisotropic shear coefficients C44 and C55 within the three layers of myocardial fibers (i.e. the epicardial, myocardial, and endocardial). We found that there was significant variation within the shear coefficients indicating that the heart is, at a minimum, orthotropic, with stiffness values ranging from 40-60 kPa.

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Keywords

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