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Abstract #1928

Radial Golden Angle Fast Spin Echo: A Hyperpolarized 13C Multi Contrast Metod

Christoffer Laustsen1, 2, Steffen Ringgard1, Henrik Birn3, Michael Pedersen1, Jan Henrik Ardnekjaer-Larsen4, 5

1MR Research Centre, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark; 2Danish Research Centre for Magnetic Resonance, Hvidovre Hospital, Hvidovre, DK, Denmark; 3Department of Biomedicine, Faculty of Health Sciences, Aarhus University, Aarhus, Denmark; 4GE healthcare, Broendby, Denmark; 5Department of Electrical Engineering,, Technical University of Denmark, Kgs. Lyngby, Denmark

We here present a new multi contrast MRI sequence for 13C-labeled hyperpolarized agents, for angiographic, perfusion and relaxation mapping, with reduced motion artifacts. Radial imaging using the golden angle, 111.25&[deg], has been utilized for free breathing MR and has successfully been used for 3He MR of lungs, where the longitudinal T1 relaxation and RF calibration yields quantitative difficulties. Hyperpolarized pulse sequences should be designed to utilize the magnetization especially efficient. In this study we employ a slice selective radial fast spin echo (FSE) sequence to show the urea transport in the kidney cortex. Further, we used the center of k-space readout for RF self-calibration and T2 mapping.

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