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Abstract #1571

Preoperatively Evaluating the Correlation Between Pathological Grades and Blood Oxygenation Level-Dependent MRI in Clear Cell Renal Cell Carcinomas

Jie Chen1, Jiule Ding1, Changping Wu2, Wei Xing1, Jingting Jiang2, Tongbing Chen3, Jun Sun1, Yongming Dai4, Ewart Mark Haacke5, Jiani Hu5

1Radiology, Affiliated Third Hospital of Suzhou University, Changzhou, Jiangsu, China; 2Oncology, Affiliated Third Hospital of Suzhou University, Changzhou, Jiangsu, China; 3Pathology, Affiliated Third Hospital of Suzhou University, Changzhou, Jiangsu, China; 4Siemens Healthcare China, MR Collaboration NE Asia, Shanghai, China; 5Radiology, Wayne State University, Detroit, MI, United States

Many treatment options exist nowadays in the management of renal rell carcinomas. Preoperative evaluation of clear cell renal rell carcinomas (CRCC) grades is important for deciding therapy. We used oxygen level-dependent magnetic resonance imaging to evaluate the correlation between R2* values and CRCC grade. Our results demonstrated that R2* values of low-grade tumors were lower than that of high-grade tumors and there was a positive relationship between R2* value and CRCC grade. Moreover, T2*-weighted images can detect intratumoral hemorrhage more sensitively than conventional T1- and T2-weighted MRI, thus offering improved accuracy by reducing the influence of hemorrhage on R2* values.

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