Meeting Banner
Abstract #1506

MR Elastography of the Liver in Patients Status Post Fontan Procedure: A Pilot Investigation

Suraj D. Serai1, Daniel Wallihan1, Sudhakar K. Ventakesh2, Richard L. Ehman2, Daniel J. Podberesky1

1Radiology, CCHMC, Cincinnati, OH, United States; 2Radiology, Mayo Clinic, Minnesota, MN, United States

After the Fontan procedure, the circulation of blood depends on high central venous pressures required for an effective transpulmonary gradient, thus generating adequate blood flow into the lungs in the absence of a subpulmonary pumping-chamber. Over the long-term, cellular atrophy, necrosis and fibrosis ensue, commonly referred to as congestive hepatopathy. MRE is a non-invasive technique that can be used as a tool to identify liver fibrosis. With the ultimate goal of applying MRE for improving current diagnostic capabilities used in the care of these patients, this proof-of-principle study provided us with valuable information that we have used in preliminary studies.

Abstract PDF Poster PDF

Keywords

additional adult adulthood affecting assessing assessment become biopsy candidates cardiac cirrhosis clinic cohort completion complication congestion considered correlation currently detected determine drawing duration early elevated etiology evaluate evaluating example expanded feasibility feasible fibrosis gold halted hence hepatic history horizon hypertension improve included increasing increasingly invasive investigation known length liver livers long many maps mayo measure measured measures mild minutes needed neoplasm operation outcomes patients pediatric physiology pilot population portal post preliminary presence procedure prognosis progresses progression quantitatively radiology ranging reaching related relatively representative retrospective reversed rises risk screening session since situations slowed status stiffer stiffness studied suggesting surgery surveillance take term tool towards transplantation trend undergoing ventricle years