in vitro and in vivo 19-Fluorine Magnetic Resonance Imaging (MRI) of β-Cells and Pancreatics Using GLUT-2 Specific Contrast Agents

Keywords

according achieved acquisition administration affected agar agents allow animals applications arch assessment atoms attempts background biomedical bladder body build built cancer cell cells chem chemical clearance coil coils comparable complete compound concentration concentrations confirmed confirms contrast derivatives detectability detection determine diabetes emerged equivalent example excited experimental expressed expressing external fast feasible fibroblasts final flash fluorine function glucose glut hallmark hereby highest highly homogenized hours immediately improved in vivo indicate indicated inhibited injection inner insulin intensity introducing islets isolated kidney known labeled labeling laboratory larger linear liver localization loop made makes male mass minutes models mosaic mouse noise organs overlaid overnight pancreas pancreatic phantom post potentially preventing production profile project protocol quantification quantitative rapid reached receive relationship remaining removed resolution saddle samples secretion sensitivity several shape slice slices solenoid solution specificity spectra spectrometer spectroscopy stage stimulation studies sufficient surface suspensions synthesized system targeting tissue transmit transporter tunable understand uptake validated viability vitro whole wise