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Abstract #1389

Novel Results from Cardiac Magnetic Resonance Imaging in a Spider Species

Gavin D. Merrifield1, Nichola M. Brydges2, Lynsey S. Hall3, Jim Mullin4, Lindsay Gallagher4, Romain Pizzi5, William M. Holmes4

1Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, Midlothian, United Kingdom; 2Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom; 3School of Molecular and Clinical Medicine, Royal Edinburgh Hospital, Edinburgh, United Kingdom; 4Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom; 5Zoological Medicine Ltd, Dunfermline, United Kingdom

To assess the potential of existing MRI scanner performance to evaluate novel model animal species cardiac MRI was performed on large spiders. The acquired images were used to extract the first direct in vivo measurements of cardiac function in this type of animal. Measurements revealed a previously unknown relationship between animal mass and cardiac ejection fraction.

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Keywords

abdomen alternative anatomical animal animals anomalous array assessing atypical audience axial basic behavior biochemical biological biomedical body bottom brain broadly cardiac cardiovascular carried channel cine cinematic clinical coil college contouring contrast correlation dedicated designed diastolic ejection enough environment evaluate example exhibited expanding expectations familiar finding flash flexible fraction fractions full function gated hall handful heart hearts history hospital human improved in vivo indicates inside institute interfering investigated investigation kingdom life limited literature live manual marked mass matrix mechanical medical medicine model modern molecular motion movement near novel onwards output physiological physiologists positioning possess potential prevent procedure producing proxy psychology pulse quantitative rearing researchers restrained restraints retrospectively rodent rough royal scanned scanner scanners scanning school science sciences scientists self slice slices species spider spiders stresses subject subjects substitutes successfully suggesting suggests survived systolic target technology traditionally trend underwent useful usual utility veterinary volumes whereas whether wider yield zoological