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Abstract #1357

Real-Time Prospective Adjustment of Inversion Time Using Arrhythmia Insensitive Inversion Recovery (AIIR) Algorithm for Delayed Hyper-Enhancement MRI

Ramkumar Krishnamurthy1, Amol Pednekar2, Jouke Smink3, Benjamin Cheong4, Raja Muthupillai4

1Rice University, Houston, TX, United States; 2Philips Health Care, Houston, TX, United States; 3Philips Health Care, Best, TX, Netherlands; 4St. Luke's Episcopal Hospital, Houston, TX, United States

A novel arrhythmia insensitive inversion recovery (AIIR) algorithm for myocardial viability imaging is presented. This algorithm can track the magnetization regrowth of tissue of interest and prospectively calculate the inversion time required to minimize artifacts arising due to variation in the normal heart sinus rhythm. Benefits of this algorithm can be felt especially in following scenarios: 1) Limited patient breath-holding capacity, 2) Severe Arrhythmias, 3) Longer duration Respiratory motion compensated scans (3D and high spatial resolution) that encounter more RR intervals per acquisition. Phantom validation and patient results demonstrate the superiority of the AIIR algorithm.

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Keywords

ablation accurately acquisition adjustment administration application appropriate around arrhythmia arrhythmias artifacts assuming axis beats best better blinded breath brighter cardiac cardiologist care circulation clinical clinically coll combination commercial compensation confirmed consistently constraint contrast correct covering crosses cumulative delayed develop diagnostic distribution drift enhancement ensure entire equal equations every excellent experienced exploited extended extent gated gradient guidance guided health heart human hyper immediately improved infarction initial injury insensitive instr intensity interval intervals inversion irreversible just kinetics linear locker longer longitudinal look magnetization make males maximal minutes myocardial myocardium nature navigator need null nulling overall paired patient patients phantom phantoms predictions preparation prior prospective prospectively protocol providing pulse quality radiology real recovery reduces regular reproducibly resolution review rice scar scarred score scout severe shot significantly simulated simulations slices software spatial steady studies subjects substantial temporal tissue tracked tracking triggered twofold types typically useful validation variable variation various vascular viability volume window world years