Meeting Banner
Abstract #1354

Carotid Pulse Wave Velocity Quantification with Non-Gated, Velocity-Encoded Projections

Zachary Rodgers1, Erin K. Englund1, Michael C. Langham1, Jeremy F. Magland1, Felix Wehrli1

1Radiology, University of Pennsylvania, Philadelphia, PA, United States

Carotid pulse wave velocity (cPWV) was quantified by combining a dual-slice excitation phase-modulated sinc pulse with velocity-encoded projections to resolve flow waveforms in the inferior and superior carotid artery at 5 ms temporal resolution. This approach does not require gating and can quantify cPWV in just seconds. cPWV was measured in three young healthy males four times each. Overall mean (SD) cPWV and path length were 6.2 (1.9) m/s and 12.4 (2.2) cm respectively. Future work will focus on improving waveform post-processing and determining the utility of cPWV as an early marker of vascular changes leading to carotid atherosclerosis.

Keywords

acquisition ages aging agree aorta aortic applying array arrival arterial arteries artery association automatically bandwidth better body cardiovascular care carotid cause characteristic coil coils common complex coronal decrease decreases defined determine determining diagram disease distance distances dual eager elevated encoded encoding ensure equal establish evaluate excitation excite existing feasibility findings flow gated gating hardy health healthy heart hold illustrates imply in vivo independently indicated individuals insufficient interestingly investigating investigation length limitation literature location locations magnitude making males marker markers measure measured modulated morbidity mortality necessary neck need otherwise overlap pair pairs particular path pathologic permitting placement planning portion potential previously processes processing progresses progression projection projections proper pulse quantification quite radiology rather real relationship reported reproducibility resolution resolved resolving robust scanned segment segmental separation simultaneously slice slices spanned spans spine stack studies subject subjects suggesting superior support table taken taking temporal toggled tree upper utility vascular velocity vessel vessels wave waveform waveforms yields