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Abstract #1339

Assessment of Energy Loss in Aortic Stenosis and Age-Matched Controls Using Bayesian Multipoint Phase-Contrast MRI

Christian Binter1, Robert Manka1, 2, Simon H. Suendermann3, Verena Knobloch1, Sebastian Kozerke1, 4

1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; 2Dept. of Cardiology, University Hospital Zurich, Zurich, Switzerland; 3Division of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland; 4Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom

Phase-contrast MRI offers the possibility to obtain both velocities and Turbulent Kinetic Energy, making it possible to quantify the energy loss due to aortic stenosis. In this work patients and age-matched controls are compared and test-retest variability is investigated. 4D flow measurements with multiple encoding velocities in the aortic arch of 3 patients and 18 healthy volunteers were performed. The results show that the physiological range of TKE in the ascending aorta shows only little variation with age and significant differences between patients and healthy controls were found.

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Keywords

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