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Abstract #1318

Comparison of Reconstruction Methods for Accelerated Cardiac MR Stress Perfusion After Physical Stress with Supine Ergometer

Christophe Schlke1, 2, Sbastien Roujol1, Murilo Foppa1, Ernest V. Gervino1, Kraig V. Kissinger1, Beth Goddu1, Sophie J. Berg1, Sebastian Kozerke2, Warren J. Manning1, 3, Reza Nezafat1

1Medecine, BIDMC / Harvard Medical School, Boston, MA, United States; 2Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; 3Radiology, BIDMC / Harvard Medical School, Boston, MA, United States

Physiologic stress provides unique information regarding a patients exercise capacity and hemodynamic response to exercise. To perform post physiologic stress CMR perfusion, we employed an MR-compatible supine ergometer mounted on the scanner table. In our experience, coil sensitivity maps are generally corrupted due to patient motion during exercise and significant respiratory motion is encountered during the CMR perfusion acquisition. To allow CMR perfusion with elevated heart rate image acquisition should be shortened. The aim of this study was to compare reconstruction methods for accelerated CMR perfusion immediately post physical stress.

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Keywords

accelerated acceleration achieve achieved acquisition address allow allows alternating amplification analyzed apparatus approaches array artifacts assessment available beat best beth better biomedical blinded blood bore calibrated capacity cardiac channel clinically coil compatible compressed constraints content corrupted dynamic elevated employed encountered engineering estimating evaluated every exam excellent exercise fashion fast feasibility full generated head healthy heart immediately improved improvement increments initial injection inversion issue jointly limit lode magnet maps medical middle minimal minimization minutes monitored motion mounted moved myocardial needs noise nonlinear optimized outer outside patient pattern perfusion physical physiologic poor post pressure prospective protocol protocols quality radiology random randomly rank rapidly reach reconstructed reconstruction recovery regarding regularization regularized resistance resolution respiratory response rhythm sampling saturation scale scanner school score scored sense sensing sensitivities sensitivity seven sharpness shortened signed significantly slices space statistical stress subjects substantial successfully superior supine table target targeted term throughout undergoing underwent uniform upper variation warren yang years