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Abstract #1310

Conversion-Free Interleaved Black Blood and Bright Blood Imaging (CfIBBI) Sequence for Dynamic Contrast Enhanced (DCE) MRI of Vessel Wall

Tingting Wu1, Huijun Chen1, Jinnan Wang2, Juan Wei3, Feiyu Li4, Chun Yuan1, 5

1CBIR, School of Medicine, Tsinghua University, Beijing, China; 2Clinical Sites Research Program, Philips Research North America, Briarcliff Manor, NY, United States; 3Philips Research Asia, Shanghai, China; 4Peking University First Hospital, Beijing, China; 5Dept. of Radiology, University of Washington, Seattle, WA , United States

In this study, a conversion-free interleaved black blood and bright blood sequence (cfIBBI) is developed for Dynamic Contrast Enhanced (DCE) MRI of vessel wall perfusion of early lesion, which has high spatial resolution and excellent blood suppression in black blood image as well as high temporal resolution in bright blood image for AIF. Moreover, the signal intensities of the black-blood and bright-blood images are comparable and can be used directly in kinetic analysis without conversion.

Keywords

abdominal absolute according accurately achieve acquisition analyzed aorta approval arrows arterial artery avoid better black blood board bright catch channel china clearly clinical coil coincident combining comparable complex concentration consistency constant contours contrast conversion curve curves custom delineated designed detect developed diagram difficulty diseased distinct drawn dynamic early enhanced especially evaluate every example excellent except expand experience extract flow frame free function generate hand healthy hence ideal identically injected institutional intensities intensity interference interleaved inversion kinetic knee lesion lesions linear longitudinal lumen magnetization manually match matrix maximal medicine minimal model moreover muscle normalized north offers partial perfusion plaque plasma post precludes program progression pulse pulses rabbit radiology rapidly reasonable recovery replace reported require resolution resolutions respectively review saline saturation scanned school segment segmented segments selective several similarly simplified simultaneously sites slice slowly solution spatial suppression system temporal thin third timing tissue traditional transform unlike vessel volume wall walls wide yuan zero