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Abstract #1300

Correlation of Atherosclerotic Disease Between Extracranial and Intracranial Carotid Artery in Symptomatic Patients: A 3.0T MR Vessel Wall Imaging Study

Xu Han1, Jianming Cai1, Danqing Liu1, Lin Ma1, Youquan Cai1, Xihai Zhao2

1Department of Radiology, PLA General Hospital, Beijing, China; 2Center for Biomedical Imaging Research & Department of Biomedical Engineering, Tsinghua University, Beijing, China

This study investigated the correlation of atherosclerotic disease between intracranial and extracranial carotid arteries using MR multicontrast, high resolution, black-blood vessel wall imaging. We found that there was significant correlation between intracranial and extracranial atherosclerotic diseases. We also found that there was significant correlation for severity of atherosclerotic disease between intracranial and extracranial circulations. Our findings further compel the evidence that atherosclerosis is a systemic disease that usually impacts multiple vascular territories and suggest that atherosclerotic plaque at extracranial carotid artery might be an indicator for either presence or severity of intracranial atherosclerosis.

Keywords

absence acquisition active addition among angiography anterior array arrows arteries artery atherosclerosis axial bandwidth beds bifurcation bilateral biomedical black blood body calcification carotid cerebral channel characteristics china circulation circulations coexisting coil common compel component compositional compositions correlated correlation coverage diffuse disease diseases divided double either engineering established events evidence example experienced features field findings general head hospital hundred hypothesized identified impacts incidence increasing indicator inflammatory intensity internal inversion investigate investigated involving length lesion lesions longitudinal matrix measure measured middle might none occur occurring panel particularly patient patients perfusion plaque plaques presence previous project quadruple radiologist radiology recent reconstructed recorded recovery recruited respectively scanner severe severity side sides significantly similarly slice sought stroke studied studies suggest symptomatic systematic systemic territories train trend underwent unilateral usually vascular vessel view wall white whole workstation yellow yuan