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Abstract #1167

Reduced Functional Connectivity of the Executive Network Predicts Mild Cognitive Impairment in Parkinsons Disease

Maryam Abaei1, Stefan T. Schwarz1, Nara Dashdorj1, Nin Bajaj2, Dorothee P. Auer1

1Radiological & Imaging Sciences, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 2Neurology, University Hospitals of Nottingham, Nottingham, Nottinghamshire, United Kingdom

Parkinson's Disease, Resting State, fMRI, Functional Connectivity, Dorsal Attention Network,

Keywords

abnormal abnormalities abnormality activity aimed allele allowing allows approved assess assessment attention blood blue brain carriers clinical cognitive coherence component components concatenation connectivity controls convergent corrected correction correlation correlations cortex demented dementia dependent disease diseases distinct divergent dorsal dual dysfunction dysfunctional episodic epsilon established evaluation evidence executive explain explore expressed extent extraction feature features fields filtering findings fluctuations form free freezing frequency frontal full function functional gait health hospitals identified impairment importantly included increasing individual inferior informed interconnected interrelations kingdom known learn little lobule longitudinal male maps matrix memory mild motion motor natl neglect network networks nucleus orienting oscillatory overlaid oxygenation parietal part participants particular patients patterns perception performance permutation posterior powerful precede preceding predicted predicts preliminary processed prominent radiological reduced reflecting regionally regression relevant removal resting retest reveals sciences score sign slice smoothing spatial spontaneous stimuli strong structures subjects suggests superior template temporal threshold tool track underwent whether years young