Wei Huang1,
Ziyu Cao1, Liqing Yang1, Shuxia Wang1,
Lifeng Gao1, Hao Lei1
1State
Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan
Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan,
Hubei, China
Type 1 diabetes is a chronic disease characterized as insulin deficiency and the resultant metabolic disturbances.It often accompanied with many complications, including diabetic encephalopathy.In this study, we measured volumetric changes in the brain of STZ-induced diabetic rats at 12 and 20 weeks using VBM. Progressive atrophy of STZ-induced diabetic brain was assessed.