Meeting Banner
Abstract #0946

An in vivo Tree Shrew Brain Anatomical Imaging Template for Tissue Segmentation and Morphormetry Analysis

Shuxia Wang1, Dai Shan1, Xuxia Wang1, Yong Fan2, Yuanye Ma3, Hao Lei1

1State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, Hubei, China; 2National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China; 3Laboratory of Primate Neurosciences, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China

Tree shrews are special relatives of primates from evolution. They are visually oriented animals with well-developed visual system and also possess developed limbic brain structures. For years, they were used as animal models in studies of visual system and social tress. However, few previous studies have used magnetic resonance imaging to study the brain of tree shrew. As an important step to achieve automated/parametric analysis of tree shrew brain imaging data, we built a set of brain tissue probability maps (grey matter, white matter and cerebrospinal fluid) of Tupaia belangeri chinensis and used for semi-automated volumetric measurements of limbic brain structures.

Keywords

academy access achieve agreed anatomical anesthesia animal animals ants applications applied atomic automated automation axial back bilateral body brain brown built china chloral chosen chronic coil collected comp constructed contiguous correction covering derived detection developed diameter drawn evolution fluid food foundation front generate grants housed hydrate important in vivo individual individually initial institute intensity inverse laboratory limbic male manual manually mapped maps materials mathematics matrix measured ministry models molecular national natl natural original parametric pattern physics pixels population preprocessed previous primate primates probability processed psychosocial pulse quadrature rare reception recognition reduced register registered registration removed reported representing resolution rigid scanner science sciences segmentation segmented semi seven shrew shrews slices social software space special springer step stress structures studies supported surface system technology template templates tissue toolbox traced transformation transmission tree uniformity vision visual volume volumes volumetric water weighed weighing white whole years zoology