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Abstract #0896

Regional Changes of Cortical Thickness and Cortical Surface in Children Born Prematurely and Children Born with Intrauterine Growth Restriction at School Age

Lana Vasung1, Laura Gui1, Elda Fischi-Gomez1, 2, Cristina Borradori-Tolsa3, Franois Lazeyras4, 5, Petra Susan Hppi1

1Division of Development and Growth, Department of Pediatrics, University of Geneva, Geneva, Switzerland; 2Signal Processing Laboratory 5(LTS5), cole Polytechnique Fdrale de Lausanne (EPFL), Lausanne, Switzerland; 3Division of Development and Growth, Department of Pediatrics, University of Geneva and University Hospital Geneva, Geneva, Switzerland; 4Department of Radiology, University of Geneva and University Hospital Geneva, Geneva, Switzerland; 5Center for Biomedical Imaging (CIBM), Geneva and Lausanne, Switzerland

The growing incidence of prematurely born children with or without intrauterine growth restriction and the improvement of survival rates has been associated with highly problematic long term neurodevelopmental outcomes. Brain structural alterations, associated with these mainly cognitive difficulties, most likely involve cortical organization. This study presents new ways of assessing structural organization of the cortex through thickness and surface measurements in children born prematurely with or without intrauterine growth restriction at the school age.

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Keywords

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