Meeting Banner
Abstract #0768

Comparison of Sequences for MR-Based Cortical Bone Imaging and Tissue Classification in the Pelvis at 3.0T with Subsequent Generation of Electron Density Maps and Digitally Reconstructed Radiographs

Michael Helle1, Christian Stehning1, Melanie S. Traughber2, Nicole Schadewaldt1, Heinrich Schulz1, Steffen Renisch1, Stefanie Remmele3

1Philips Research Laboratories, Hamburg, Germany; 2Philips Healthcare, Cleveland, OH, United States; 3Hochschule Landshut (FH), Landshut, Germany

Emerging MRI applications, e.g. radiation therapy planning, benefit from superior display of tissue contrast and the delineation of tumor and critical organs. However, utilizing MRI for standalone radiation therapy simulation would require the generation of electron density (ED) maps and segmentation of cortical bone for the creation of digitally reconstructed radiographs (DRRs). In this study, we introduce a new approach based on a Cartesian T1-Dixon acquisition for tissue classification and cortical bone imaging to generate ED maps and DRRs of the pelvis at 3.0T. Results of a Cartesian T1-Dixon acquisition are compared qualitatively with a combined UTE-multi-echo Dixon sequence.

Keywords

acquisition adipose adjusting adjustment affecting allow allowed applicability application applications approaches array arrays artifacts assignment atlas attenuation background basis benefit body bone bowel bulk calibrated cart cavities characterized classification coil combined combining compartments components compromises construction content contents contrast cortical critical delay delineation density derived differentiation digitally edge elaborate electron element emerging enhanced enhancement errors false fast field filtered filtering five fractions generate generated generation good gradient growing hamburg head healthy hybrid induced introduce investigated just known laboratories lack made makes manual manually maps markedly mask mater materials misclassification moreover nearly noise noisy optimal outer overcome pelvic pelvis planning post preparation probabilistic problem processing propagates qualitatively quality radial radiation receive reconstructed reconstruction reduce related remains removal representative require requires residual sampling seems segment segmentation segmenting since slices slight soft standalone step structures subsequent subtraction suffer superior switching system systems terms therapy thereby thresholding tissue tomography trajectory trans triple tune utilizing water