Meeting Banner
Abstract #0649

Quantification of Ventilation and Perfusion Using Non-Contrast Enhanced Quasi-Randomly Acquired DC Gated 1H Lung Imaging

Andr Fischer1, Christian O. Ritter1, Stefan Weick2, Dietbert Hahn3, Herbert Kstler1

1Institute of Radiology, University of Wuerzburg, Wuerzburg, Bavaria, Germany; 2Department of Experimental Physics 5, University of Wuerzburg, Wuerzburg, Bavaria, Germany; 3Institute of Radiology, University of Wrzburg, Wuerzburg, Bavaria, Germany

This abstract describes the quantification of pulmonary perfusion and ventilation using non-contrast enhanced quasi-randomly acquired DC gated 1H lung imaging. By properly selecting data according to the DC gating signal which reflects signal variations induced by respiration and pulsatile blood flow, images of the respiratory and cardiac standard cycles are obtained. From these, quantification of perfusion (by a concept called AQUAPICSS) and ventilation (by comparing expiration to inspiration signal levels) is possible. Perfusion rates are in accordance with literature values and additionally performed SEEPAGE experiments. Ventilation rates were derived in normal amplitude respiration and are, therefore, lower than previous literature values obtained in maximum amplitude respiration.

Abstract PDF Presentation Video

Keywords

absence absolute abstract according acquisition actual additionally agents allow amplitude anatomical aorta applied approaches approximation assumption beginning blood bottom breath breathing calculating called cardiac cause central clinical combination combined comparable completely concept contrast convolution correspond corresponds covering currently cycle cycles datasets decomposition dependent depends depicting derived describe described determination determined deviation diagram direct directly drawn early enable enables enabling encoding enhanced entered entering experimental expiration external feasible flow functional furthermore gated gating healthy hence hold holds identified included individual induced informed inspiration intervals iterative literature lung magnetization maps moreover nature need newly note paragraph parallel peaks perfusion physics please plug procedure promising pulmonary pulse pulses quantification quantified quantify quantitative quasi radiology randomly reaches recently reconstructed reconstruction reduced removes resolved resp respiration respiratory scanner seepage seven short simple since slice spins steady steps take taking theoretical triggering trio uncooperative undergoing upper variations velocity ventilation vessels visible visualized volunteer volunteers width window windows