Meeting Banner
Abstract #0466

Improved T1 Relaxometry with NMR Field Probes: Demonstration of Contrast Agent Characterization

Simon Gross1, Benjamin E. Dietrich2, Christoph Barmet2, 3, Klaas P. Prssmann2

1Institute for Biomedical Engineering, , University and ETH Zurich, Zurich, Switzerland; 2Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; 3Skope Magnetic Resonance Technologies, Zurich, Switzerland

The observation of longitudinal nuclear magnetization with NMR field probes is a fast and sensitive method for the characterization of T1-relaxation times. Changes in the properties of the NMR field probes and geometrical considerations lead to an increase in sensitivity of a factor of ten. A field measurement resolution of 50 pT was reached, enabling robust and precise fitting of signals acquired in single shot experiments.

Abstract PDF Presentation Video

Keywords

added adding adiabatic affected agent allowing although amplitude applied approaches around assessments bandwidth biological biomedical built calibration capability concentration confidence confounds consists constraints contrast curve curves cylindrical decay demonstration desirable detected determination deviation dilution dipole direct duration dynamics ease efficiency elaborate enabled enables engineering epoxy equal error exceedingly expected exploited exponential extensions fairly field fields fitted fitting fixed fold geometry gross highest improved indicated induced inhomogeneities initial inside interval inversion issue kept liquid lobes longitudinal magnetization matched maximized measure measured must nearly neither noise novel nuclear numerical observation occurs overall overshoot perfect picture polarized positions precision previous probe probes prolonged proportional publication pulse pulses punished pure quality reached readout reason reduced reported requiring resolution respectively robust sample samples scanner sensitivity series setup shimming shot sign simplicity simulated simulation simulations since solenoids static studied sufficient suppressing susceptibility technologies temperature temporal thermal trading tried typically uncertainty usually versus vicinity volume water whose wind