Meeting Banner
Abstract #0211

Dual-Echo Diffusion-Weighted EPI for Better Sensitivity to Acute Stroke

Samantha J. Holdsworth1, Stefan Skare2, Kristen Yeom1, Michael U. Antonucci1, Jalal B. Andre3, Jarrett Rosenberg1, Matus Straka1, Nancy J. Fischbein1, Greg Zaharchuk1, Roland Bammer1

1Department of Radiology, Stanford University, Palo Alto, CA, United States; 2Karolinska Institute, Clinical Neuroscience,, Stockholm, Sweden; 3Department of Radiology, University of Washington, Seattle, WA, United States

Here we investigate an alternative approach to diffusion-weighting imaging (DWI) with the use of a parallel-imaging enhanced dual-echo sequence. It was found that dual-echo DWI is a powerful method for evaluating diffusion-restricting lesions. The long echo time of Echo 2 gives rise to DW images that exhibit superior sensitivity to diffusion lesions than DW images acquired at a shorter echo time; Echo 1 provides high SNR ADC maps for specificity to acute stroke; and the information from both echoes is a potential source of complementary information for the assessment of blood and mineralization products.

Abstract PDF Presentation Video

Keywords

accelerated acceptable achieve acute additional advanced alone alternative alto apparent applicability arrow arrowhead arrows assess assessment attention audience avoid basal best better blood brings calcification candidate chronic clinical closed coefficient coil common complementary confidence confirming considered contradicting contrast correlating dead deemed delineation detecting detection diagnosed diagnostic diffusion done draw dual echoes enhanced evaluated evaluation exploited favored foundation furthermore ganglia gives good graded head heightened hemorrhage hypothesize identification impacted impression improve improving infarct infarcts influenced institute interleaves investigated lesion lesions long longer many maps matrix mineralization open outstanding overall partial patient patients poor potential potentially practice practitioners predicted products prolonged protocoling radiological radiologists radiology rank ratings recommend related respectively restricting reveal reviewed rise routine ruling scale scanner sensitivity setting shine short shorter signed since source specificity stroke superior surrounding suspected tailed target teaching technology tissue typically unanimously useful workup