Hyperpolarized Singlet Lifetimes of Pyruvate in Human Blood and in Mouse

Keywords

according acid acquisition aimed albeit allow although alto amount animals apparent approved arises audience benefit biomedical blood body bond bore buffer cancer carbons chelate clinical completion compliance concentration configuration constants coupled creating decay delay described detect detected detection diluted dioxide direct dissolution dissolved doubly dual energy equivalence excitation expected experiment exploiting extending fast field final fold framework fully human immediately in vivo initial injected injection inserted instruments intervals investigated kingdom lactate lifetime lifetimes limited little live local longer magnet maintained metabolic metabolism metabolites molecules mouse nuclear observations occurring outside oxford oxygenated patients place polarization predictions preservation preserved preserving presumably procedure procedures produced product project promising proof prostate prototype pulse radical radiologists reaction reactions realized redistribution reduction repetition review samples satisfy scientific seventh shorter since singlet singly sixty slice slow species spectra spectral spectrum spin start subject substrates superheated support system table taken takes target tissue transport trial triplet tuned typically unity volume whole