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Abstract #2141

Connectivity-Based Segmentation of the Precuneus in Individual Adolescent Rhesus Macaque DTI Data.

Elizabeth Zakszewski1, Nagesh Adluru1, Ned Kalin1, Andrew L. Alexander1

1University of Wisconsin-Madison, Madison, WI, United States

Connectivity-based segmentation of the precuneus, an important connectome hub, is performed on DTI data of young rhesus monkeys. We observe how the proportion of connections from the precuneus to functionally different brain regions (limbic, somatosensory, and visual) shifts with increasing age. This gives us valuable information for creating models of brain development.

Keywords

academic added adolescent adolescents allows among anatomical animals appear appears applied assigned atlas attention bilateral brain carries children coefficients combined compute connected connection connections connectivity consciousness consistent continuous contours cook correlation corresponds cortex cortical counted create created creating decline density development developmental diffusion distribution dominated elliptical episodic estimation examined example fisher fraction fractions function functional functionally functions general generated greatest holes humans implicated important index individual insights interaction iterations iteratively known lateral least limbic linear located macaque major many medial memory mental models monkey monkeys movement occipital others overlay parietal parker part parts pattern patterns percentage plotted population posterior press probabilistic probability procedure processed proportion registered regression represent representation retrieval review rhesus robust roughly seed segment segmentation segmented selection self sensory significance since slice smallest solid spatial squares starting stat statistical streamlines strongest subjects subregions tailed template temporal tensor together trajectories transformation trends units visual volume volumes years