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Abstract #0541

Comparison of Noncontrast FSD MRA to Time Resolved (TWIST) and High Resolution Contrast Enhanced MRA of the Hands in Patients with Systemic Lupus Erythematosus (SLE) and Clinical Vasculopathy.

Rola Saouaf1, Zhaoyang Fan2, Mariko L. Ishimori3, Lindsy J. Forbess3, Emmanuil Smorodinsky1, Daniel J. Wallace3, Michael H. Weisman3, Debiao Li2

1Imaging, Cedars-Sinai Medical Center, Los Angeles, CA, United States; 2Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States; 3Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, United States

Systemic Lupus Erythematosus (SLE) is an autoimmune disease which can affect hand vasculature. Noncontrast FSD MRA was compared to contrast enhanced (CE) Time resolve (TWIST) and high resolution MRA. Vascular pathology was compared to clinical findings. Preliminary data shows FSD MRA was superior to CE MRA in all segments evaluated. Vascular pathology had variable concordance with clinical presentation which will warrant further investigation.

Keywords

absent acquisition affect affected affecting allowing angiography arches arterial arteries artifacts autoimmune barely better bilateral biomedical body bodyweight caliber cedars clinical coils common complications confounding contamination contrast coronal decreased depicted dermal diagnoses diagnosing diagnostic differentiation digital digits diminished disease document edema enhanced evaluating evaluation excellent exploration extent findings flow function gadolinium gain good gradient hand hands hyperemia impaired includes increasing indicated inherent injected insufficiency invest involvement irregularity known lesions limited limiting lupus male manifestations medical meeting mild motion nearly nephritis none noninvasive objective often ongoing optimal overestimation palm patient patients perceived physician poor predominantly promise promising proof proper prospectively quality questionnaires radiologists ranging recorded recruited relatively renal resolution respectively ring risk sandwiched segment segments severe severity significantly soft spatial stations statistical strength subject subjective subjects suggesting suggests superior susceptible symptomatology symptoms systemic table technical terminal terminus timing tiny tissue tufts twist typically ulceration ulnar utilized vascular venous vessels visualization visualized year