Meeting Banner
Abstract #4476

Phospholipid Fingerprints of Milk from Humans and Different Animal Species Determined by 31P NMR: Importance for Human Health

Cyrielle Garcia1, Norbert W. Lutz2, Sylviane Confort-Gouny2, Patrick J. Cozzone2, Martine Armand1, Monique Bernard2

1UMR INSERM UF476/INRA1260, Universit Aix-Marseille, Facult de Mdecine, Marseille, France; 2CRMBM UMR CNRS 6612, Universit Aix-Marseille, Facult de Mdecine, Marseille, France

Phospholipids (PLs) play key roles in signaling pathways, inflammatory processes and lipid digestion. Milk contains PLs as important compounds that likely have positive health effects. We present an optimized 31P NMR spectroscopy protocol for comparing PLs in human milk vs. milk from cow, mare and camel, based on milk extracts. 12 PL classes were quantified, 6 of which were rather concentrated. Camel milk was particularly rich in PLs in general and in sphingomyelin and plasmalogens in particular. Thus, in arid countries camel milk appears as a promising dietary source due to the cardioprotective, hepatoprotective and brain protective effects of PLs.

Abstract PDF E-Poster Video

Keywords

absorption acetic adult adults agreement among amount anal analyzed animal animals appears approximately arid available benefits best bilayers boxes brain breeding briefly broader camel cell centrifugation characterized chemical classes collected components concentrations consequence considerably consistently consisting containing content countries cows deconvolution decoupling delay described detectable determination determined determining dietary digestion dynamic efficient either evaporated extracted extracts fifth fingerprints greatly health highest horizontal human humans identified importance important increasingly indicated infants inflammatory ingested instance integrated least lipid lipids literature lowest mare mature measure measuring medians membrane methanol methylene milk minimal mixture moreover newborns nitrogen optimized organic particular pathways pattern percentiles pooled positive potentially practical premature preparation previously processes profile profiles promising protocol published pulse putative rather regards replace represent resolution respect respectively richer sample samples significance significantly since software solution source sources species specimens spectra spectrometer spectroscopy stored studies subclasses synthesis system table term thermally twelve twice varied volumes waltz whiskers width