Development of a Robust MR-Compatible 5mm Bioreactor for Primary Human Tissue Cultures and Hyperpolarized MR

Keywords

able achieved acquiring adaptation aggressiveness allows analogous application assess assessed biochemical cancer cartridge cell cells chamber characterization clinically combinations compatible confirmed constants construct conversion cost critical cross culture cultured cultures custom degradation demonstrating density design designed development dissolution dramatically dynamic encapsulated encapsulation enclosed engineering equipped experiment explore extend feasibility fixed flow flux fluxes focused fold formalin goal harvested hours human immortalized inhibitor injected injection instruments interfaced kinetics label lactate limited linked long maintain maintained mark mechanical medium metabolism million minimal model nature nearly necessary normalized novel nuclear nuclei ongoing optimize oxford oxygen oxygenated peak penicillin perfused perfusion platform polarization potential preservation preserved primary probe providing pulses radiology real reduced relaxed relevant renal require requirements requires response robust robustly secs sectioned slice slices solution spectra status stem structural structure studies subsequently sufficient supplemented system systems technology term therapy tissue tissues traditional translating turn type typical utilized variables variety verifies viability volume volumes