Meeting Banner
Abstract #4468

How to Achieve a 100% Success Rate in Cardiac 1H MR Spectroscopy

sa Carlsson1, 2, Maja Sohlin2, Maria Ljungberg1, 2, Eva Forssell-Aronsson1, 2

1Department of Medical physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden; 2Department of Radiation Physics, University of Gothenburg, Gothenburg, Sweden

Localised proton MR-spectroscopy can be used for lipid quantification in the human myocardium but it is difficult as the method suffers from both motion and large susceptibility effects. It is, however, possible to achieve a 100% success rate in healthy volunteers and obtain good spectral quality every single time if following a strict measurement protocol where every step is optimised for each individual. The three most important steps were: 1) Planning the VOI completely within the ventricular septum, 2) using navigator triggered field mapping for shimming, and 3) optimising the cardiac triggering time delay using spectroscopy.

Keywords

abstract achieve acquiring acquisitions aged alter axis beam biomedical blood body breath breathing called cardiac cells challenging chamber channel chosen cine clear coil completely completion considered consisted consistently contamination content cycle deadline degrade delay delays describe described development difficulties earlier efficient engineering enough equipped evaluation every expiration facilitates field final free frequently full getting gives good healthy heart hospital human increasingly independent individual individually inferior lead leads likely lipid localization localized lungs magma many mapping maria medical metabolism minimize motion myocardium navigator need noise outline package peak pencil physics planned planning poor poorly popular position positioned preliminary protocol proton quality quantification radiation reduce repetitive resolved respiratory scanned separate separation septum shim shimming short since spectra spectral spectroscopy spectrum starting step steps stored strategy strict subjects succeeded success successful suffers summation supine suppressed surrounding susceptibility system systems systole tool transmission triggered triggering triglycerides user variation ventricular verifying volume volunteers water whole years