Methylphenidate's Effects on the Metabolomic Profile of the Rat Brain Measured by 1H-MRS

Keywords

accentuated acquisition acquisitions activity administered administration adult anesthesiology anesthetized animals application applied arterial attention basal black blocking blood body brain brook central cerebral challenge challenges characterized children coil complex concentration concentrations conditions consequence correlates course custom decrease decreased decreases deficit demand demonstrating depressing designed disorder dopamine dose drug either equipped excitation excitatory experiment exposed female flow gases glucose glutamate grant heart human hyperactivity independent individuals institute instrument internal intravenous invasive juveniles laboratory lack lactate lasted ligands long macro made measured mechanically medical metabolic metabolism metabolite metabolites mixture model molecular monitoring national nervous neuronal optical oxygen parallel pharmacological physiological placebo positron post preservation pressure procedure profile proton quantified radioactive rats recorded reduction report representative representing respiratory response rodent routinely saturation sensors short significantly slight slightly smith spectra spectral spectrum spontaneously status stimulant stony studies supported surface synaptic system term thought tomography transient transiently transporters treated treatment unsuppressed valuable ventilated view volume young