Meeting Banner
Abstract #4422

Accelerated In-Vivo Liver 31P MRSI Using GRAPPA

Anshuman Panda1, 2, Scott Jones1, 2, Rahul Srinivasa Raghavan1, Keith Heberlein3, Radhouene Neji3, Ulrike Dydak1, 2

1School of Health Sciences, Purdue University, West Lafayette, IN, United States; 2Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States; 3Siemens Healthcare, Erlangen, Germany

31P magnetic resonance spectroscopic imaging (MRSI) of the human liver is of clinical interest but requires long scan times. We investigated the feasibility of accelerating in-vivo 31P MRSI of the human liver using GRAPPA and a dual tuned 8-channel 31P/1H coil. Successful implementation of 31P GRAPPA MRSI on the scanner allowed for reduction of the scan time for 2D 31P MRSI data across a whole liver slice from 25.75 min to 15.17 min, while maintaining quantifiable spectral data quality and alias-free metabolite maps. It was concluded that acceleration of 31P in-vivo liver MRSI is feasible using GRAPPA reconstruction.

Keywords

able abundance acceleration acquisition aliasing allowed amplitude another applying array assessed authors away axial bandwidth bottom calibration carboy central channel clinical close coil concentration denotes ding dual experiment extending farther fast feasibility feasible generalized generate grant health human in vivo investigate liver locations longer loss magneto male maps metabolite metabolites minimal nominal panda parallel partially peak phantom phonic pilot plastic plates potassium potential radiology read remove retained sample scanner school selective separately setup significantly slice smaller solution space spectra spheres stacked studies successful system thank took trio tuned uniform validation volunteer weigh west whole wing