Volumetric Quantitation of Metabolic Kinetics of Hyperpolarized [1-13C]pyruvate Using Multiband RF Pulses

Keywords

achieve achieving acquisition acquisitions activities affected alanine amplitude analyzed animals apparent applied applies appropriate approximately bolus brindle built chemical choice close coil coincident combined consistent constant conversion described design designed desirable determined dirk dual duration dynamic effective efficient electrical eliminate employing engineering every example excitation excitations exciting exists extension formulation gradient grant healthy hence heterogeneity important inflow inflowing injected injection injections instruments international investigation keeping kidney kinetics labeling laboratory lactate length like liver longitudinal magnetization match matched maximal mayer measured measuring metabolic metabolites model modeled modeling molecular nominal nuclear obviates operating organs oxford park pathologies pathology peak performance polarization precisely prior products pulse pulses quadrature quantification quantified radiology rats reaction real receive relying representative resolution ripple samples sampling saturation scale scaled scanner scheme select shot slab slice slices solution spatial spectral spectroscopic spin spins spiral started steps summarizes table tail thick transit transmit unbiased variable various velocity volume volumetric waveform window