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Abstract #4091

Quantification of Renal Lipid and Oxygenation in Diabetic Mice by Magnetic Resonance Imaging

Shenghong Ju1, Xin-gui Peng1, Gao-jun Teng1

1Department of Radiology, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China

To study the feasibility of in vivo MR measurement of lipid accumulation and oxygenation in kidney using the diabete (db/db) mouse model

Keywords

abnormal accumulation acid adipose administration advantages amount association atmosphere blood bold boxes cells characterized chemical china chronic comparing compartments content contents control correlation cortex decreased dependent deposits detect detectable developing development diabetes diabetic diseases distribution droplets dynamic energy enlargement epithelial evaluated evidence example examples exhibited expansion exposure extracellular feasibility function growing hospital hypoxia in vivo increasing indicated indicates induced infusion injection injury inner inserted kidney linear lipid lipids localized location longitudinally magnification major maps matrix measure measured medulla metabolism mice model mostly mouse nature nitrogen noninvasive novel outer oxygen oxygenation pathogenesis people periodic play post potential potentially progression protons pure quantification quantitative radiology renal republic reserve respiration reviews role saturation scanner selecting selection selective significantly southeast staining strong subcutaneous suggested suggesting target tissue treatments tubular type useful visceral volume water white whole wild