Molecular Imaging of Non-Alcoholic Fatty Liver Disease Using an Endogenous Hyperpolarized Redox Sensor

Keywords

abnormality accumulation acids address ahead alcoholic antioxidant application believe biomedical capacity care cell characterization choline coil conversion correlate correlates custom decrease decreased decreases deficient demonstrating depletion deregulation described develop developed development diabetes diet disease dissolution dual electron enzymatic equipped experimental export extend extent fatty final findings fold form free generation genetic hepatic impacts implicated in vivo incidence indicative induced injected injury instruments insufficient integrals invasive isotropic journal leakage lifetime lipid liver livers manipulation many maps matrix methionine mice micro millipede mitigate model models molecular mouse nearly nuclear obese onset overload oxford oxidant oxidation oxidative package patients peak percentage peroxides placed polarization post potential prevalent previously print prior probe processed progression proteins radiology reach readily readout recent recognized reduced reduction remarkable resolution response rodent sacrificed scheme sensor sign significantly software spin sponsors staining stress strongly structure studies subsequent target therapeutics therapy tissue transported treatment tuned validated variable visible visual visualized vitamin water weeks written