Early Alterations in Cerebral Oxygen Extraction in Autosomal-Dominant Alzheimer's Disease

Keywords

absolute acquisition alterations although amount appeared approximation assumed available background blood brain buckles candidate caused cerebral chance children combined compensate concentration consistent controls correlation cortex currently cylinder damage decrease decreased defects delivered dementia determined developing disease displays divided dominant drains early expected explained extraction fairly field filtering findings flow form forms fraction generations genes genetic gradient human ideal ideally identify implies important importantly included includes indicate individual individuals inherited investigated investigations john knight lead maintaining majority markers measure measured medicine metabolism modifying morris motivated mutation mutations near necessarily neurological neurology nominal normalization normalizes nuclear occur occurred ongoing onset overall oxygen parent parental part pass passed patient patients pediatrics population portion posterior previous prior process produces progression progressive project radiology reconstructed removed represents resolution school severe sinus straight studies subjects substantial superior susceptibility symptoms taken therapies ultimately uncorrelated view