Diffusion Tensor Imaging Analysis with Tract-Based Spatial Statistics of the White Matter Abnormalities in Early-Treated Phenylketonuria

Keywords

ability abnormal abnormalities abnormality accumulation acid aligned amino analyses anisotropy anterior apparent axial body brain byproduct capsule characterized cluster coefficient cognitive compromise condition consistent continue continued controls corona corpus corrected correlation cortical created cross dawn decreased derived dietary diffusion diffusivity disruptions distributed dopamine early equally examining experienced external fiber finding findings forceps fractional genetic green healthy hypotheses hypothesized impaired impairments importantly inadequate individuals inferior intracellular investigate larger longitudinal many maps measured mechanism mechanisms metabolism metabolize minor needed negative neurotransmitters numerous occipital onto overlaid oxford participant participated past patient patients permutations pervasive phenylalanine post posterior precise precursor prior procedure produced projected radiate recent reduced reduces related relationship relied replicate reported represents restrictive revealed sample scanner selection shot significantly skeleton space spatial spin statistical statistics status studies subject subjects suggested suggesting suggests superior suppl tensor thinned threshold tract tracts treated treatment trio turnover tyrosine unclear underlying utilizing vectors visualized water whereas white worsen