MRI Biomarkers Capable of Detecting Effects of an Experimental Pharmacologic Therapy for Idiopathic Normal Pressure Hydrocephalus

Keywords

able abnormalities absence affected approaches around arterial artifacts automatically blood brain broad brought capable carbonic cerebral check chosen city clearance clinical clinically cognitive college combination consistent corpus costly daily days decrease decreased defined designed detect detected detecting diagnosed diffusion diffusivity disorder distributed disturbance done dose doses drug edema efficacy elevated enlargement establish even excite experimental feasible female findings flair flow fluid gait guiding healthy heather hydrocephalus hypo hypothesized identical idiopathic important incontinence indicating inhibitor initial intensities interleaved interstitial isotropically known label lateral male markers matrix medical metrics much needed neurosurgery ongoing otherwise overall participants pathology patient patients percentage pilot planar play poles pressure production properly proven quantitative reduce reduced reducing reduction registered reliable remaining represent rest role scanner scanning school screen selected series slices smith spin starting suggest suitable symptomatic task tensor therapeutic therapy thick treatment treatments trials undertaken unequivocally unnoticed urinary ventricles ventricular volume volumetric volunteer water whether wise years