Meeting Banner
Abstract #3556

Effect of Registration on Fractional Anisotropy Values

Kurt Hermann Bockhorst1, Priya Goel1, Ponnada A. Narayana1

1DII, University of Texas, Houston, TX, United States

Registration is commonly used during the post processing of medical imaging data. However, the effect of registration on the quantification of imaging metrics as DTI has not been reported recently. The submitted abstract documents a significant decrease of FA values (up to 20%) in the white matter (splenium and genu) of rat brains after registration. We studied this phenomenon with four different types of registration: AIR, FSL, DTI-TK (tensor based) and ANTS. All of these methods caused a significant decrease in FA.

Abstract PDF E-Poster Video

Keywords

acquiring adult affect always analyzed anatomical anesthetized animal animals anisotropy ants appears applied assist atlas averaging bipolar blood brain breathing caution coil common commonly constantly corpus created cross derived described diffusion digital disease efficacy elsewhere even exercised five fixed fractional frequency generally gray house humans icosahedral identification identifying improve in vivo independent individual influence interpolation interpreting introduce investigated investigating involves male manager manually many material matrix maximal measured measures medical mode monitored much neighboring objectively orientation oxygen partial placing preprocessed protocol pulse quantitative rats recording rectal reduced reduces reduction registered registering registration relatively requires resolution rodents scanner shot significantly signs smith spatial specifically spin structures studies suggest suppl surface temperature template tensor treatment type types unregistered various vital volume volumes woods